Health
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How to fight depression? Faster.
Hope flags when medications fail, isolating and endangering patients. Backed by a major grant, 2 Harvard scientists are focused on reducing the distance between diagnosis and recovery.
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Threat of mosquito-borne diseases rises in U.S. with global temperature
Experts fear more cases of West Nile virus, EEE (and possibly Zika, Dengue fever) as warm seasons get longer, wetter
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Seem like peanut allergies were once rare and now everyone has them?
Surgeon, professor Marty Makary examines damage wrought when medicine closes ranks around inaccurate dogma
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3 million Americans have dental implants — but procedure wasn’t always ‘routine’
Surgeon recounts changes in field over 40-year career — from titanium screws to bone regeneration — as he accepts Goldhaber Award
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Getting to the bottom of long COVID
A reservoir of virus in the body may explain why some people experience long COVID symptoms
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‘Heartbreaking’ encounter inspired long view on alcohol
One encounter changed everything for researcher who hopes to help mothers and families detect and treat the effects of dangerous drinking
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Pain promoter plays unexpected role in central nervous system
Despite all the attention it draws in patients, pain has only in recent years been deemed a subject worthy of scientific scrutiny.
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Accomplice fingered in cholera toxicity
A study published in March 2001 revealed one of the ways that cholera toxin hijacks some of the cell’s own machinery. In uncovering part of the toxin’s trail, a team…
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Non-smoking bar and restaurant workers inhale as much as active smokers
Working in a bar or restaurant can expose you to as much tobacco smoke as if you were an active smoker, a researcher based at the Harvard School of Public…
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Strict enforcement of lead-exposure-prevention policies shows clear benefits
Even at low levels, lead poisoning in children can cause IQ deficiencies, reading and learning disabilities, impaired hearing, reduced attention spans, hyperactivity and other behavior problems. Children who live in…
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Cancer cells’ immortality may depend on longevity protein
A team of Harvard Medical School researchers has identified a protein that 10 percent of tumor cells use to attain an immortal state. By blocking the molecule, it may be…
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Human genome tally: Is recount in order?
The surprising finding that humans have fewer genes than expected led to endless speculations and editorial comments. Would biotech stocks be threatened? Should humans be more humble? Were entirely new…
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Nonsmoking college students 40 percent less likely to take up smoking when they live in smoke-free dorms
Although 81 percent of colleges prohibit smoking in all public areas, only 27 percent prohibit smoking in students’ dormitories. Harvard School of Public Health researchers say the finding sends a…
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Rules for music wired into the brain
“Music is in our genes,” says Mark Jude Tramo, a musician, prolific songwriter, and neuroscientist at Harvard Medical School. “Many researchers like myself are trying to understand melody, harmony, rhythm,…
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Testing to identify drug-resistant AIDS strains is cost-effective
A new study led by the Harvard Center for Risk Analysis, published in the Annals of Internal Medicine in March 2001, finds that testing people with HIV to determine whether…
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Surgery without scalpels
Paul Simmons, a 29-year-old Maine farmer, suffered from a lung tumor. In February 2001, at Harvard-affiliated Brigham and Women’s Hospital in Boston, a probe containing a long needle was inserted…
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Medicare patients give higher overall marks to nonprofit health plans
The first large-scale national study that examines the relationship between health plan characteristics and patient ratings of their plan found that Medicare patients prefer not-for-profit or local plans over for-profit…
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Majority of Alzheimer’s plaques cleared from brains of living mice
Harvard Medical School researchers, working with scientists at Elan Pharmaceuticals, cleared 70 percent of Alzheimer’s plaques from the brains of mice by applying anti-plaque antibodies directly to the mouse brains…
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Brain hesitates in assembling mosaic of motion
Your brain must integrate information from many different neurons in the primary visual cortex to interpret movement. But how does this complicated process work? Richard Born and Christopher Pack of…
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Lyme disease vaccine found cost-effective only for those at high risk
Lyme disease, a bacterial infection transmitted through deer tick bites, is rapidly emerging in the U.S. and currently affects about 15,000 people each year. But incidence varies widely according to…
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Simulating disease trends with massive mathematical models
Researcher Karen Kuntz is currently developing a model to evaluate trends in colorectal cancer incidence and mortality. Nearly 50,000 Americans die each year from the disease, despite the fact that…
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How embryonic stem cells become fine-tuned brains
Research by Michael Greenberg, Harvard Medical School professor of neurology at Children’s Hospital, begins to explain how the embryonic brain’s stem cells decide whether to mature into nerve or glial…
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Gene initiates joint formation
Researchers at Harvard Medical School have identified a molecule that plays a central role in the initiation of joint formation. Studying limb formation in the developing chick, postdoctoral fellow Christine…
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In human genome race, competition spurred better science
The conflicts between the two teams — one publicly funded, one private — that raced to sequence the human genome often drew more attention than the actual completion of the…
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New vaccines could balance global burden of disease
The scientific community believes that diseases that have long plagued the world can be controlled by vaccination. But vaccines won’t work unless they reach the people who need them most…
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Growth factor seen to reverse loss of muscle from aging, disease
Previous work by Nadia Rosenthal of Harvard Medical School and her colleagues showed that injection of a virus directing the expression of a molecule known as insulin-like growth factor I…
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T-cell response to HIV proteins may make them vaccine candidates
Development of a vaccine against HIV-1 has long focused on the virus’s structural proteins. These molecules are expressed relatively late in the viral life cycle, after HIV-1 has decreased the…
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Specific gene provides health benefits for moderate drinkers
Moderate alcohol consumption among people who have a specific version of a gene that metabolizes alcohol yields health benefits — less risk of heart disease and higher good cholesterol levels.…
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Increased consumption of soda promotes childhood obesity
Soft drinks are currently the leading source of added sugars in the daily diet of young Americans. Now, researchers have conducted the first long-term study to examine soda consumption and…
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Increased fruit and vegetable consumption does not reduce risk of breast cancer
A recent Harvard study examined the association between fruit and vegetable consumption and breast cancer. The researchers drew participants from eight separate studies that spanned four countries and involved more…
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Cloak partly lifted on tiny Chlamydia
The Boston Public Health Commission released 1999 statistics showing 2 percent of the city’s 15- to 19-year-olds have chlamydia. Boston’s minority girls were reported to have infection rates of almost…
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Direct damage from radiation may be passed to neighboring cells
Cells communicate, organize, share resources, and form direct connections with one another. They also are affected by damage to their neighbors. Research led by John Little of the Harvard School…
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Surprise route found for spread of breast cancer
Cancer cells are thought to enter the lymph nodes through the lymphatic system — a multipurpose welter of vessels — but how the cells actually make their way out of…
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Studies show new players and patterns in vertebrate heart development
Cell biologists have identified proteins capable of promoting heart development — at least in frogs and birds. They report that the proteins Dkk1 and Crescent, which inhibit regulatory proteins of…
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Fat cells tied to whole-body insulin resistance
Research done by Barbara Kahn, professor of medicine at Beth Israel Deaconess Medical Center, and colleagues now shows that glucose uptake by fatty tissue is important for maintaining the body’s…
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New gene found in fruit flies could impact human medicine
In one type of fruit fly, Drosophilia melanogaster, but not in others, researchers found a gene that carries instructions for making a motor that gives this species’ sperm extra horsepower.…